Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.60 |
| ▸ | AHR | P35869 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017064 | 0.86 | AHR (0.53) | KIF11AHRHSD17B10NR4A2CYP2A6 | |
| SCHEMBL7084999 | 0.85 | NPC1 (0.62) | KIF11AHRHSD17B10NR4A2CYP2A6 | |
| SCHEMBL29355842 | 0.83 | KIF11 (0.65) | KIF11AHRHSD17B10CYP2A6GPR84 | |
| SCHEMBL45243 | 0.83 | KIF11 (0.65) | KIF11AHRHSD17B10CYP2A6GPR84 | |
| SCHEMBL5720438 | 0.81 | AHR (0.57) | KIF11AHRNR4A2CYP2A6F7 | |
| SCHEMBL25026080 | 0.81 | KIF11 (0.47) | KIF11AHRHSD17B10NR4A2CYP2A6 | |
| SCHEMBL30375508 | 0.81 | CYP17A1 (0.54) | KIF11AHRHSD17B10NR4A2CYP2A6 | |
| SCHEMBL30375749 | 0.81 | CYP2A6 (0.53) | KIF11AHRNR4A2CYP2A6S1PR1 | |
| SCHEMBL30376017 | 0.81 | KIF11 (0.47) | KIF11AHRHSD17B10NR4A2CYP2A6 | |
| SCHEMBL30375432 | 0.81 | HDAC1 (0.48) | KIF11AHRNR4A2CYP2A6F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561735-A | Compound with anti-glioma activity, preparation method and application thereof | 海南大学 | 2024-08-30 | — | — | CN | claimed |
| CN-118056825-A | Vilazodone derivative, synthesis method thereof and application thereof in preparation of antitumor drugs | 复旦大学附属肿瘤医院 | 2024-05-21 | — | — | CN | claimed |
| US-12559480-B2 | Methods of treatment using phenyl indole allosteric inhibitors of P97 ATPase | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2026-02-24 | — | — | US | disclosed |
| US-20260034105-A1 | Generative AI-Assisted Identification of Novel PI3K-alpha Inhibitors | THE FIRST AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIVERSITY (CN) | 2026-02-05 | — | — | US | disclosed |
| EP-4629988-A1 | DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS | Centre National de la Recherche Scientifique (FR) | 2025-10-15 | — | — | EP | disclosed |
| US-20250230127-A1 | MONO- OR DI-SUBSTITUTED INDOLE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS | JANSSEN PHARMACEUTICALS INC (US) | 2025-07-17 | — | — | US | disclosed |
| US-12358878-B2 | N-aromatic amide compounds, preparation methods and uses thereof | SHENZHEN EDK PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2025-07-15 | — | — | US | disclosed |
| US-20250171452-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. | 2025-05-29 | — | — | US | disclosed |
| CN-119823020-A | Preparation method of 3-thiocyanatoindole derivative | 常州工程职业技术学院 | 2025-04-15 | — | — | CN | disclosed |
| CN-119775261-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-4514804-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | Viscient Bio, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| EP-0912556-B1 | INDOLINE DERIVATIVES USEFUL AS 5-HT-2C RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-10-04 | — | — | EP | disclosed |
| WO-2000017198-A1 | 3-BICYCLOINDOLE COMPOUNDS AS 5-HT1D LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-03-30 | — | — | WO | disclosed |
| EP-0912556-A1 | INDOLINE DERIVATIVES USEFUL AS 5-HT-2C RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-05-06 | — | — | EP | disclosed |
| US-5834494-A | SEROTONIN 5HT2B/2C RECEPTOR ANTAGONISTS; CNS NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS; IRRITABLE BOWEL SYNDROME | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-11-10 | — | — | US | disclosed |
| WO-1997048700-A1 | INDOLINE DERIVATIVES USEFUL AS 5-HT-2C RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-12-24 | — | — | WO | disclosed |
| EP-0707581-B1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-02-26 | — | — | EP | disclosed |
| EP-0707581-A1 | INDOLINE DERIVATIVES AS 5HT 2C? ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001976-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-01-19 | — | — | WO | disclosed |
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559480-B2 | Methods of treatment using phenyl indole allosteric inhibitors of P97 ATPase | TMEM97, ADRM1, ABCB11 | KIF11 1890/4885AHR 152/4885HSD17B10 2088/4885 |
| US-20260034105-A1 | Generative AI-Assisted Identification of Novel PI3K-alpha Inhibitors | PIK3R1, PIK3R4, PIK3R2 | KIF11 4594/4885AHR 419/4885HSD17B10 946/4885 |
| US-20250230127-A1 | MONO- OR DI-SUBSTITUTED INDOLE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS | IDO1, IDO2, IRF3 | KIF11 2517/4885AHR 429/4885HSD17B10 3734/4885 |
| US-20250171452-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | IDO2, IDO1, TPSB2 | KIF11 4545/4885AHR 91/4885HSD17B10 2363/4885 |
| US-12358878-B2 | N-aromatic amide compounds, preparation methods and uses thereof | H1-3, H1-0, NAT1 | KIF11 3336/4885AHR 34/4885HSD17B10 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.