Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325287 | 1.00 | ALDH1A1 (0.55) | ALDH1A1KDM4EPKMLCKMEN1 | |
| SCHEMBL8680186 | 0.83 | MEN1 (0.55) | ALDH1A1PKMMEN1KMT2AHPGD | |
| SCHEMBL8327239 | 0.83 | MEN1 (0.55) | ALDH1A1PKMMEN1KMT2AHPGD | |
| SCHEMBL8327237 | 0.83 | MEN1 (0.55) | ALDH1A1PKMMEN1KMT2AHPGD | |
| SCHEMBL976424 | 0.78 | MAOB (0.73) | MEN1KMT2AHPGDCYSLTR1MRGPRX4 | |
| SCHEMBL30412034 | 0.78 | MAOB (0.73) | MEN1KMT2AHPGDCYSLTR1MRGPRX4 | |
| SCHEMBL9366619 | 0.78 | P4HB (0.65) | ALDH1A1KDM4EPKMMEN1KMT2A | |
| SCHEMBL9366613 | 0.78 | P4HB (0.65) | ALDH1A1KDM4EPKMMEN1KMT2A | |
| SCHEMBL8408179 | 0.77 | HDAC1 (0.53) | ALDH1A1PKMMEN1KMT2AHPGD | |
| SCHEMBL6495758 | 0.76 | KDM4E (0.52) | ALDH1A1KDM4EPKMLCKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |