Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325282 | 0.87 | MAPT (0.46) | MAPTSMN1; SMN2MAPK1HTTRAB9A | |
| SCHEMBL20884918 | 0.83 | KDM4E (0.51) | HTR3AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL23917111 | 0.82 | SIRT6 (0.55) | AGXTHTR3AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL11245265 | 0.81 | DRD4 (0.57) | HTR3AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL30602337 | 0.79 | AGXT (0.44) | AGXTHTR3AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL22652120 | 0.79 | GAA (0.58) | AGXTHTR3AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL423400 | 0.77 | MAPT (0.65) | HTR3AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL8318825 | 0.75 | MAPT (0.59) | HTR3AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL31204287 | 0.74 | DRD4 (0.48) | HTR3AMAPTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL22634679 | 0.73 | SIRT6 (0.66) | MAPTMAPK1SIRT6HTR6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |