Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325286 | 0.87 | AGXT (0.44) | MAPTSMN1; SMN2RAB9AHTTMAPK1 | |
| SCHEMBL8318822 | 0.76 | MAPT (0.62) | MAPTSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL8319638 | 0.76 | MAPT (0.65) | MAPTSMN1; SMN2RAB9AHTTMAPK1 | |
| SCHEMBL8318858 | 0.72 | DRD4 (0.44) | MAPTSMN1; SMN2HTTMAPK1ALDH1A1 | |
| SCHEMBL2874038 | 0.71 | ADRB1 (0.59) | HTTADRB1THRB | |
| SCHEMBL20884918 | 0.69 | KDM4E (0.51) | MAPTSMN1; SMN2RAB9AHTTMAPK1 | |
| SCHEMBL23917111 | 0.69 | SIRT6 (0.55) | MAPTSMN1; SMN2RAB9AHTTMAPK1 | |
| SCHEMBL21736792 | 0.68 | L3MBTL1 (0.49) | MAPTSMN1; SMN2RAB9AHTTMAPK1 | |
| SCHEMBL16216338 | 0.68 | MAPT (0.42) | MAPTSMN1; SMN2RAB9AHTTMAPK1 | |
| SCHEMBL1989192 | 0.68 | IDO1 (0.64) | SMN1; SMN2HTTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |