Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325327 | 1.00 | S100B (0.66) | S100BPTGS2GAAMAPTKMT2A | |
| SCHEMBL28964170 | 0.87 | PTGS2 (0.65) | S100BPTGS2GAAMAPTKMT2A | |
| SCHEMBL9188784 | 0.87 | PTGS2 (0.65) | S100BPTGS2PTGS1CYP1B1CA12 | |
| SCHEMBL8321668 | 0.87 | PTGS2 (0.65) | S100BPTGS2GAAMAPTKMT2A | |
| SCHEMBL9188791 | 0.87 | PTGS2 (0.65) | S100BPTGS2PTGS1CYP1B1CA12 | |
| SCHEMBL8321666 | 0.87 | PTGS2 (0.65) | S100BPTGS2GAAMAPTKMT2A | |
| SCHEMBL8575451 | 0.86 | PTGS2 (0.58) | S100BPTGS2GAAMAPTKMT2A | |
| SCHEMBL8575456 | 0.86 | PTGS2 (0.58) | S100BPTGS2GAAMAPTKMT2A | |
| SCHEMBL8319294 | 0.86 | PTGS2 (0.69) | S100BPTGS2GAAMAPTKMT2A | |
| SCHEMBL8319299 | 0.86 | PTGS2 (0.69) | S100BPTGS2GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990137-A | ANTIINFLAMMATION AGENTS; PREVENTING THE OXIDATING BURST FROM PHAGOCYTIC LEUKOCYTES; CONTROLLING FREE RADICALS IN THE IMMUNE RESPONSE | IDUN PHARMACEUTICALS, INC. (US) | 1999-11-23 | — | — | US | disclosed |
| US-5939460-A | Method of inhibiting NADPH oxidase | IDUN PHARMACEUTICALS, INC. (US) | 1999-08-17 | — | — | US | disclosed |
| WO-1998001120-A1 | METHOD OF INHIBITING NADPH OXIDASE | IDUN PHARMACEUTICALS, INCORPORATED (US) | 1998-01-15 | — | — | WO | disclosed |