Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 9/20 | 0.61 |
| ▸ | STK4 | Q13043 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 7/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.53 |
| ▸ | RAF1 | P04049 | 3/20 | 0.51 |
| ▸ | SRC | P12931 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8561034 | 0.86 | PDE4B (0.43) | MAP2K1STK4EGFR | |
| SCHEMBL8561356 | 0.86 | PDE4B (0.44) | MAP2K1STK4EGFR | |
| Hydrochloric Acid SCHEMBL8564884 | 0.84 | MAP2K1 (0.41) | MAP2K1STK4EGFRERBB2 | |
| SCHEMBL8566080 | 0.84 | PDE4B (0.43) | MAP2K1STK4EGFRERBB2 | |
| SCHEMBL8563461 | 0.82 | PDE4B (0.41) | MAP2K1STK4 | |
| SCHEMBL8564146 | 0.81 | CSF1R (0.50) | STK4EGFRERBB2 | |
| SCHEMBL8559603 | 0.80 | DHFR (0.41) | MAP2K1STK4EGFR | |
| SCHEMBL8563378 | 0.80 | PDE4B (0.59) | — | |
| SCHEMBL8565303 | 0.80 | CSF1R (0.62) | EGFRERBB2 | |
| SCHEMBL8559490 | 0.79 | CSF1R (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | disclosed |
| US-5780482-A | TREATING RHEUMATIC DISEASES | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| WO-1995000511-A1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |