Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810902 | 0.80 | BRS3 (0.47) | BRS3MEN1POLBKMT2AHRH3 | |
| SCHEMBL8319666 | 0.79 | CYP3A4 (0.48) | BRS3 | |
| SCHEMBL1691973 | 0.76 | BRS3 (0.43) | BRS3MEN1POLBKMT2AHRH3 | |
| SCHEMBL278 | 0.73 | GPR84 (0.44) | BRS3 | |
| SCHEMBL652534 | 0.71 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28063353 | 0.71 | GPR84 (0.49) | BRS3 | |
| SCHEMBL27458278 | 0.69 | GPR84 (0.42) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9425091 | 0.69 | BRS3 (0.38) | BRS3MEN1POLBKMT2ANPSR1 | |
| SCHEMBL6251513 | 0.69 | HRH3 (0.38) | BRS3MEN1POLBKMT2AHRH3 | |
| SCHEMBL7767311 | 0.67 | HRH3 (0.37) | BRS3MEN1POLBKMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589665-B1 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA CHEMICAL IND CO LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5401736-A | Angiotensis II antagonists | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0589665-A2 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-30 | — | — | EP | disclosed |