Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 10/20 | 0.60 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22983970 | 1.00 | TYMP (0.60) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL12714672 | 0.90 | TYMP (0.59) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL31556051 | 0.90 | TYMP (0.59) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL3821714 | 0.90 | TYMP (0.59) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL2281663 | 0.90 | TYMP (0.59) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL21828784 | 0.90 | TYMP (0.59) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL31342955 | 0.88 | TYMP (0.61) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL9238078 | 0.86 | TYMP (0.58) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL32677371 | 0.86 | TYMP (0.58) | TYMPPOLA1POLBKDM4ETAS1R3 | |
| SCHEMBL9017501 | 0.86 | TYMP (0.58) | TYMPPOLA1POLBKDM4ETAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115629-A1 | CHIRAL SYNTHONS FOR THE SYNTHESIS OF CHIRAL PHOSPHOROTHIOATES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2025-04-10 | — | — | US | disclosed |
| EP-4308580-A1 | CHIRAL SYNTHONS FOR THE SYNTHESIS OF CHIRAL PHOSPHOROTHIOATES | Boehringer Ingelheim International GmbH (DE) | 2024-01-24 | — | — | EP | disclosed |
| CN-116981677-A | Chiral synthons for synthesis of chiral phosphorothioates | 勃林格殷格翰国际有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022194924-A1 | CHIRAL SYNTHONS FOR THE SYNTHESIS OF CHIRAL PHOSPHOROTHIOATES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-09-22 | — | — | WO | disclosed |
| EP-0542770-B1 | RANDOM BIO-OLIGOMER LIBRARY, A METHOD OF SYNTHESIS THEREOF, AND A METHOD OF USE THEREOF | UNIV ARIZONA (US) | 1999-01-27 | — | — | EP | disclosed |
| US-4458066-A | BOUND TO INORGANIC SUPPORT | UNIVERSITY PATENTS, INC. (US) | 1984-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115629-A1 | CHIRAL SYNTHONS FOR THE SYNTHESIS OF CHIRAL PHOSPHOROTHIOATES | TYMP, RNGTT, TYMS | TYMP 1/4885POLA1 60/4885POLB 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.