Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.53 |
| ▸ | NT5E | P21589 | 7/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320944 | 0.91 | ALDH1A1 (0.57) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL6320952 | 0.91 | ALDH1A1 (0.57) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL6320949 | 0.91 | ALDH1A1 (0.57) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL4371662 | 0.90 | ALDH1A1 (0.56) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL4371767 | 0.90 | ALDH1A1 (0.56) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL24601162 | 0.90 | ALDH1A1 (0.70) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL5406154 | 0.89 | ALDH1A1 (0.55) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL5406159 | 0.89 | ALDH1A1 (0.55) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL5406147 | 0.89 | ALDH1A1 (0.55) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8327419 | 0.89 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |
| EP-0680488-B1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LTD (GB) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996002553-A2 | AMINO PURINE-β-D-RIBOFURANURONAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1996-02-01 | — | — | WO | disclosed |
| EP-0680488-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017090-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |
| EP-0139358-B1 | N6-SUBSTITUTED DIARYLALKYL ADENOSINES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | WARNER-LAMBERT COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0251339-A2 | N6- substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same | WARNER-LAMBERT COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |
| EP-0139358-A2 | N6-substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same | WARNER-LAMBERT COMPANY (US) | 1985-05-02 | — | — | EP | disclosed |