Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.57 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121774 | 0.85 | AGTR1 (0.57) | AGTR1AGTR2ENPP2ALDH1A1LMNA | |
| SCHEMBL7853694 | 0.84 | AGTR1 (0.71) | AGTR1AGTR2ENPP2TLR7ALDH1A1 | |
| SCHEMBL8327779 | 0.83 | TP53 (0.60) | AGTR1AGTR2ENPP2TLR7ALDH1A1 | |
| SCHEMBL7850660 | 0.81 | ALDH1A1 (0.64) | AGTR1AGTR2ENPP2TLR7ALDH1A1 | |
| SCHEMBL9087992 | 0.81 | AGTR1 (0.70) | AGTR1AGTR2TLR7 | |
| SCHEMBL4957555 | 0.80 | PDE4A (0.84) | AGTR1AGTR2TLR7LMNAPDE4A | |
| SCHEMBL9851543 | 0.79 | AGTR1 (0.66) | AGTR1AGTR2ENPP2ALDH1A1LMNA | |
| SCHEMBL9044530 | 0.78 | AGTR1 (0.51) | AGTR1AGTR2ENPP2ALDH1A1LMNA | |
| SCHEMBL7851373 | 0.78 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL9043343 | 0.77 | AGTR1 (0.50) | AGTR1AGTR2ENPP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |