Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410082 | 0.92 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL8327991 | 0.92 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8323093 | 0.90 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8322426 | 0.90 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8325939 | 0.90 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL8325903 | 0.89 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8327533 | 0.89 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8327393 | 0.88 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8412385 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8327100 | 0.86 | AGTR1 (0.49) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498721-B1 | N-substituted quinoline derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1999-12-22 | — | — | EP | claimed |
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |