Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410082 | 0.95 | AGTR1 (0.49) | AGTR1AGTR2ACHETP53MAPT | |
| SCHEMBL8414576 | 0.92 | AGTR1 (0.51) | AGTR1AGTR2ACHE | |
| SCHEMBL8414575 | 0.91 | ACHE (0.47) | AGTR1AGTR2ACHETP53MAPT | |
| SCHEMBL8411067 | 0.90 | AGTR1 (0.54) | AGTR1AGTR2ACHE | |
| SCHEMBL8327093 | 0.87 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8327991 | 0.82 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8322426 | 0.81 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8410125 | 0.81 | AGTR1 (0.50) | AGTR1AGTR2ACHE | |
| SCHEMBL8323093 | 0.81 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8413697 | 0.80 | AGTR1 (0.53) | AGTR1AGTR2ACHECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |