Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324850 | 0.92 | DRD4 (0.38) | DRD4FAAHDRD2DRD3SIGMAR1 | |
| SCHEMBL8328890 | 0.92 | DRD4 (0.41) | DRD4FAAHDRD2DRD3 | |
| SCHEMBL8327903 | 0.89 | DRD4 (0.42) | DRD4FAAHDRD2DRD3SIGMAR1 | |
| SCHEMBL8327102 | 0.84 | DRD4 (0.41) | DRD4DRD2DRD3SIGMAR1 | |
| SCHEMBL8327988 | 0.84 | DRD4 (0.39) | DRD4DRD3SIGMAR1KCNH2KDM4E | |
| SCHEMBL8327984 | 0.84 | DRD4 (0.39) | DRD4DRD3SIGMAR1KCNH2 | |
| SCHEMBL8326299 | 0.83 | DRD4 (0.38) | DRD4FAAHCHRM1BCHE | |
| SCHEMBL8324935 | 0.83 | DRD4 (0.38) | DRD4DRD2DRD3SIGMAR1BCHE | |
| SCHEMBL8323149 | 0.82 | DRD4 (0.40) | DRD4FAAHSIGMAR1 | |
| SCHEMBL8327273 | 0.82 | DRD4 (0.40) | DRD4FAAHDRD2DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |