Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328677 | 0.84 | MEN1 (0.43) | MCHR1MEN1KMT2A | |
| SCHEMBL8327446 | 0.81 | MEN1 (0.43) | MCHR1MEN1KMT2A | |
| SCHEMBL8620132 | 0.78 | MCHR1 (0.36) | MCHR1MEN1KMT2AACKR3 | |
| SCHEMBL14376647 | 0.77 | MCHR1 (0.46) | MCHR1MEN1KMT2A | |
| SCHEMBL8331123 | 0.75 | ALDH1A1 (0.40) | MCHR1MEN1KMT2AACKR3 | |
| SCHEMBL8331126 | 0.75 | MCHR1 (0.38) | MCHR1MEN1KMT2AACKR3 | |
| SCHEMBL14566080 | 0.74 | TAAR1 (0.55) | KMT2A | |
| SCHEMBL8329918 | 0.71 | MCHR1 (0.37) | MCHR1MEN1KMT2A | |
| SCHEMBL8326756 | 0.71 | MAOB (0.59) | — | |
| SCHEMBL8329914 | 0.70 | MCHR1 (0.38) | MCHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |