Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328677 | 0.85 | MEN1 (0.43) | MEN1KMT2AMCHR1MAPT | |
| SCHEMBL8327315 | 0.81 | DRD2 (0.41) | MEN1KMT2AMCHR1 | |
| SCHEMBL14376647 | 0.81 | MCHR1 (0.46) | MEN1KMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL31687493 | 0.80 | MAPT (0.45) | MAPT | |
| SCHEMBL713426 | 0.78 | MAPT (0.55) | MAPT | |
| SCHEMBL3143360 | 0.75 | MAPT (0.59) | MEN1KMT2AMAPTCA2 | |
| SCHEMBL8326756 | 0.74 | MAOB (0.59) | — | |
| SCHEMBL6417812 | 0.74 | CHRM2 (0.33) | MEN1KMT2A | |
| SCHEMBL11981474 | 0.73 | MAPT (0.56) | MAPTTAAR1 | |
| SCHEMBL11767 | 0.73 | MAPT (0.52) | MAPTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |