Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324228 | 0.80 | DRD4 (0.41) | DRD4KCNH2HSD17B10KDM4EGRIN2B | |
| SCHEMBL8326479 | 0.80 | LMNA (0.46) | DRD4THRBLMNAMEN1CYP1A2 | |
| SCHEMBL8326763 | 0.74 | DRD4 (0.41) | DRD4DRD3HSD17B10KDM4EGRIN2B | |
| SCHEMBL8327397 | 0.73 | GRIN2B (0.38) | DRD4LMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL8327984 | 0.69 | DRD4 (0.39) | DRD4THRBLMNAMEN1CYP1A2 | |
| SCHEMBL8330206 | 0.68 | DRD4 (0.39) | DRD4DRD3HSD17B10KDM4EGRIN2B | |
| SCHEMBL8324935 | 0.68 | DRD4 (0.38) | DRD4LMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL8327102 | 0.68 | DRD4 (0.41) | DRD4LMNACYP2C19DRD3SIGMAR1 | |
| SCHEMBL8328890 | 0.67 | DRD4 (0.41) | DRD4LMNADRD3MAPTGRIN2B | |
| SCHEMBL8329130 | 0.67 | DRD4 (0.41) | DRD4KCNH2HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |