Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326763 | 0.91 | DRD4 (0.41) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL8325382 | 0.89 | DRD4 (0.34) | DRD4DRD2DRD3CNR2 | |
| SCHEMBL8328809 | 0.84 | POLB (0.38) | DRD4KDM4EALDH1A1CHKAMLNR | |
| SCHEMBL8327695 | 0.80 | DRD4 (0.47) | DRD4HIF1AEPAS1DRD2DRD3 | |
| SCHEMBL8324228 | 0.80 | DRD4 (0.41) | DRD4KDM4EALDH1A1KCNH2MOGAT2 | |
| SCHEMBL8330206 | 0.80 | DRD4 (0.39) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL8330663 | 0.76 | DRD4 (0.38) | DRD4KDM4EALDH1A1MOGAT2CNR2 | |
| SCHEMBL8328415 | 0.76 | GSK3B (0.36) | DRD4 | |
| SCHEMBL8328371 | 0.75 | NOS3 (0.35) | — | |
| SCHEMBL8321742 | 0.74 | PKM (0.37) | DRD4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |