SCHEMBL83274

SCHEMBL83274

Nc1ccccc1N(N)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.41
ALOX15 P16050 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
ALDH1A1 P00352 8/20 0.39
KDM4E B2RXH2 4/20 0.39
MAPT P10636 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
CYP1A2 P05177 3/20 0.39
CYP2C9 P11712 3/20 0.39
CYP2C19 P33261 3/20 0.39
CYP2D6 P10635 2/20 0.39
TSHR P16473 4/20 0.36
HSD17B10 Q99714 3/20 0.36
HPGD P15428 3/20 0.36
CHEK1 O14757 1/20 0.34
NEK2 P51955 1/20 0.34
LIMK1 P53667 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoromethane SCHEMBL27860810 0.94 CYP3A4 (0.36) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
Methyl Alcohol SCHEMBL27475139 0.94 CYP3A4 (0.36) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
Toluene SCHEMBL27633667 0.90 TSHR (0.42) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
Sulfuric Acid SCHEMBL5565767 0.88 TTR (0.38) CYP3A4SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL26198153 0.85 CYP3A4 (0.50) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
SCHEMBL2465784 0.85 ALDH1A1 (0.37) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
Tetrazole SCHEMBL17968131 0.80
SCHEMBL20888969 0.79 CYP3A4 (0.43) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
SCHEMBL17739024 0.78 LOXL2 (0.35) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
SCHEMBL30221915 0.78 ALDH1A1 (0.52) CYP3A4ALOX15SMN1; SMN2CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120082001-A High-strength low-temperature-resistant organic silicon polyurethane resin and preparation method thereof 烟台先进材料与绿色制造山东省实验室 2025-06-03 CN claimed
CN-118812988-B Light aging resistant bamboo powder bio-based degradation material for agricultural mulching film and preparation method thereof 汕头市雷氏塑化科技有限公司 2025-02-07 CN claimed
CN-118812988-A Light aging resistant bamboo powder bio-based degradation material for agricultural mulching film and preparation method thereof 汕头市雷氏塑化科技有限公司 2024-10-22 CN claimed
WO-2024120097-A1 POLYIMIDE ELECTROPHORETIC COATING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 合肥汉之和新材料科技有限公司 2024-06-13 WO claimed
CN-114103156-B System and method for producing high-elasticity-modulus high-strength glass fiber laminated board 山东玻纤集团股份有限公司 2024-05-31 CN claimed
CN-118098818-A Semi-cured composite resin magnetic film, preparation method and application 电子科技大学 2024-05-28 CN claimed
CN-117659915-A Conductive adhesive based on modified epoxy resin, and preparation method and application thereof 长春永固科技有限公司 2024-03-08 CN claimed
CN-116496466-A Polyurethane material and preparation method thereof 中国科学院兰州化学物理研究所 2023-07-28 CN claimed
CN-116102898-A Preparation method of direct blending dark blue 内蒙古新亚化工有限公司 2023-05-12 CN claimed
CN-111057260-B Preparation method of black matte polyimide film 株洲时代华鑫新材料技术有限公司 2022-12-13 CN claimed
EP-0467311-A2 Polymer scale preventive agent method of preventing polymer scale deposition using it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-01-22 EP claimed
US-4970278-A QUINONE-AMINE POLYMER, SILICA SOL OR ALKYL SILICATE KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-11-13 US claimed
EP-0317306-A2 Method of preventing polymer scale deposition Kanegafuchi Chemical Industry Co., Ltd. (JP) 1989-05-24 EP claimed
EP-0176798-B1 AMINODIPHENYL AMINES AND HAIR DYES CONTAINING THEM Henkel Kommanditgesellschaft auf Aktien (DE) 1989-01-18 EP claimed
EP-0279016-A2 Powdered hair dye HOYU CO., LTD. (JP) 1988-08-24 EP claimed
CN-86100480-A The lubricant additive that is used with Aalcohols fuel 1987-08-19 CN claimed
CN-86100790-A The high-content that is used for alcohol engine lubricating oil is peace and quiet/dispersing additive 1986-07-30 CN claimed
EP-0042725-B1 PROCESS FOR SUSPENSION-POLYMERIZING VINYL CHLORIDE TOKUYAMA SEKISUI KOGYO KABUSHIKI KAISHA (JP) 1984-09-19 EP claimed
EP-0042725-A1 Process for suspension-polymerizing vinyl chloride TOKUYAMA SEKISUI KOGYO KABUSHIKI KAISHA (JP) 1981-12-30 EP claimed
US-3936307-A Light and heat sensitive composition for producing a colored transfer complex image MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-02-03 US claimed