Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9091264 | 0.85 | LDHA (0.56) | ALDH1A1TSHRTDP1KDM4EHSD17B10 | |
| SCHEMBL27321194 | 0.85 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| SCHEMBL490808 | 0.84 | HSD17B10 (0.55) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| SCHEMBL3776630 | 0.82 | CYP3A4 (0.46) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| SCHEMBL491054 | 0.81 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| SCHEMBL3610075 | 0.79 | MAPT (0.49) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| SCHEMBL8651065 | 0.78 | HSD17B10 (0.51) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 | |
| SCHEMBL2673394 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1LMNASMN1; SMN2 | |
| SCHEMBL3761927 | 0.76 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1TDP1KDM4EHSD17B10 | |
| SCHEMBL17049174 | 0.76 | MAPT (0.55) | ALDH1A1L3MBTL1TSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050839-C | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | CN | disclosed |
| EP-0633259-B1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | HOFFMANN LA ROCHE (CH) | 1999-01-13 | — | — | EP | disclosed |
| CN-1106007-A | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | disclosed |