Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 16/20 | 0.40 |
| ▸ | RARG | P13631 | 15/20 | 0.40 |
| ▸ | RARA | P10276 | 15/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329074 | 0.87 | RARB (0.37) | RARBRARGRARANPC1CASP3 | |
| SCHEMBL8331408 | 0.87 | RARB (0.37) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL8329764 | 0.85 | RARB (0.49) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL6237093 | 0.78 | RARA (0.53) | RARBRARGRARA | |
| SCHEMBL27554945 | 0.74 | RARB (0.45) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL9007121 | 0.71 | RARA (0.43) | RARBRARGRARANPC1CASP3 | |
| SCHEMBL9007048 | 0.70 | RARA (0.37) | RARBRARGRARANPC1CASP3 | |
| SCHEMBL8331925 | 0.69 | RARA (0.48) | RARBRARGRARANPC1CASP3 | |
| SCHEMBL6242265 | 0.69 | RARA (0.66) | RARBRARGRARA | |
| SCHEMBL8331061 | 0.68 | RARB (0.49) | RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| US-5952345-A | RETINOID ACID RECEPTOR ANTAGONIST; A DERIVATIVES OF ARYL-SUBSTITUTED AND ARYL (3-OXO-1-PROPENLY)-SUBSTITUTED BENZOPYRAN, BENZOTHIOPYRAN, 1,2-DIHYDROQUINOLINE; PREVENTING TOXICITY OR SIDE EFFECTS CAUSED BY RETINOIDS OR VITAMIN A | ALLERGAN SALES, INC. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5877207-A | SKIN DISORDERS; ANTICARCINOGENIC AGENTS | ALLERGAN SALES, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5776699-A | MEASURING GENE EXPRESSION | ALLERGAN, INC. (US) | 1998-07-07 | — | — | US | disclosed |