Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.48 |
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | RARG | P13631 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | JUN | P05412 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329764 | 0.80 | RARB (0.49) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL6591846 | 0.76 | RARA (0.48) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL8328688 | 0.75 | RARA (0.52) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL6589052 | 0.72 | RARA (0.47) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL8327478 | 0.69 | RARB (0.40) | RARARARBRARGRAB9ANPC1 | |
| SCHEMBL8331408 | 0.69 | RARB (0.37) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL9007048 | 0.69 | RARA (0.37) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL8331030 | 0.68 | RARA (0.48) | RARARARBRARGKMT2ARAB9A | |
| SCHEMBL9007121 | 0.68 | RARA (0.43) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL6590745 | 0.67 | RARA (0.40) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |