SCHEMBL8327508

SCHEMBL8327508

CCN(CC#Cc1ccc(C2CCCC(Cl)C2)cc1)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
GLA P06280 1/20 0.32
CYP2C19 P33261 1/20 0.32
CNR2 P34972 5/20 0.31
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27468419 0.78 SLC6A4 (0.32) CNR2
SCHEMBL27466038 0.78 SIGMAR1 (0.35) ALDH1A1GLACYP2C19CNR2
SCHEMBL8327501 0.76 SIGMAR1 (0.39) CNR2
Hydrochloric Acid SCHEMBL7314180 0.75 SIGMAR1 (0.38) CNR2
SCHEMBL27502462 0.72 CYP2C19 (0.40) CYP2C19CNR2
SCHEMBL8329039 0.70 ALDH1A1 (0.35) ALDH1A1GLACYP2C19
SCHEMBL8652251 0.66 ALDH1A1 (0.38) ALDH1A1GLACYP2C19CNR2
Hydrochloric Acid SCHEMBL7324538 0.65 ALDH1A1 (0.40) ALDH1A1GLACYP2C19CNR2
Hydrochloric Acid SCHEMBL7517080 0.64 ALDH1A1 (0.32) ALDH1A1GLACYP2C19
SCHEMBL27482621 0.61 DRD2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0917464-A1 USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION SANOFI (FR) 1999-05-26 EP disclosed
WO-1998004251-A1 USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION SANOFI (FR) 1998-02-05 WO disclosed