Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 13/20 | 0.66 |
| ▸ | NOS1 | P29475 | 8/20 | 0.66 |
| ▸ | NOS3 | P29474 | 6/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7052386 | 0.86 | NOS2 (0.60) | NOS2NOS1NOS3 | |
| SCHEMBL7051205 | 0.80 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL7048509 | 0.78 | NOS2 (0.77) | NOS2NOS1NOS3 | |
| SCHEMBL7048505 | 0.78 | NOS2 (0.77) | NOS2NOS1NOS3 | |
| SCHEMBL7049660 | 0.78 | NOS2 (0.77) | NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL7049243 | 0.76 | NOS2 (0.61) | NOS2NOS1NOS3 | |
| SCHEMBL5672165 | 0.76 | NOS2 (0.48) | NOS2NOS1NOS3 | |
| SCHEMBL8327998 | 0.75 | NOS2 (0.69) | NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL7052284 | 0.75 | NOS2 (0.60) | NOS2NOS1NOS3 | |
| SCHEMBL8328239 | 0.75 | NOS1 (0.37) | NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972975-A | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |