Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992475 | 0.74 | ANPEP (0.53) | ANPEPCA12CA9HTR2AMEN1 | |
| SCHEMBL28816482 | 0.74 | SMN1; SMN2 (0.54) | ANPEPHTR2ARETHTR2CHRH1 | |
| SCHEMBL8327028 | 0.73 | RAB9A (0.36) | ANPEPCA12CA9MEN1CYP3A4 | |
| Bromide SCHEMBL4989971 | 0.73 | ANPEP (0.52) | ANPEPCA12CA9HTR2AMEN1 | |
| SCHEMBL27543841 | 0.73 | HTR2A (0.48) | ANPEPHTR2ARETSMN1; SMN2 | |
| Bromide SCHEMBL30630619 | 0.73 | ANPEP (0.52) | ANPEPCA12CA9HTR2AMEN1 | |
| SCHEMBL1567832 | 0.72 | HTR2A (0.46) | ANPEPHTR2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL14061414 | 0.71 | CA12 (0.56) | CA12CA9 | |
| SCHEMBL7539000 | 0.66 | IDO1 (0.43) | HTR2ARETHTR2CHRH1MYC | |
| SCHEMBL14581370 | 0.66 | CA12 (0.68) | CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529636-B1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1999-06-23 | — | — | EP | disclosed |
| US-5436250-A | Isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1995-07-25 | — | — | US | disclosed |
| US-5242918-A | Isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-07 | — | — | US | disclosed |
| WO-1993005043-A1 | NOVEL ISATINOXIME DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 1993-03-18 | — | — | WO | disclosed |
| EP-0529636-A1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-03-03 | — | — | EP | disclosed |