Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 9/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320427 | 0.90 | HDAC2 (0.56) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL8325359 | 0.82 | CA12 (0.43) | — | |
| SCHEMBL8323871 | 0.78 | HDAC2 (0.55) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL8323151 | 0.77 | HDAC1 (0.54) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL8323117 | 0.77 | HDAC1 (0.52) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL8319501 | 0.76 | THRB (0.54) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL13960334 | 0.75 | HPGDS (0.61) | — | |
| SCHEMBL3291655 | 0.74 | HDAC2 (1.00) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL3291661 | 0.74 | HDAC2 (1.00) | HDAC2HDAC8HDAC1HDAC3HDAC6 | |
| SCHEMBL14244759 | 0.72 | HDAC2 (0.89) | HDAC2HDAC8HDAC1HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |