Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604523 | 0.77 | YTHDC1 (0.36) | NPSR1KDM4EATMTDP1SLC18A3 | |
| SCHEMBL14873970 | 0.77 | KDM4E (0.41) | CCR5NPSR1KDM4EATMTDP1 | |
| SCHEMBL6393397 | 0.72 | SLC6A2 (0.49) | — | |
| SCHEMBL761128 | 0.71 | TSHR (0.45) | KCNH2ALDH1A1OPRM1OPRL1LMNA | |
| SCHEMBL8327042 | 0.69 | SLC18A3 (0.34) | CCR5KCNH2NPSR1KDM4EATM | |
| SCHEMBL1238800 | 0.67 | OPRM1 (0.39) | ATMSLC18A3OPRM1 | |
| SCHEMBL2504679 | 0.67 | AOC3 (0.41) | NPSR1ALDH1A1 | |
| SCHEMBL22553534 | 0.66 | SLC18A3 (0.41) | CCR5NPSR1KDM4EATMTDP1 | |
| SCHEMBL22553535 | 0.66 | SLC18A3 (0.41) | CCR5NPSR1KDM4EATMTDP1 | |
| SCHEMBL15191721 | 0.66 | SLC18A3 (0.41) | CCR5NPSR1KDM4EATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |