Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14873970 | 0.78 | KDM4E (0.41) | SLC18A3DDB1CRBNNPSR1KDM4E | |
| SCHEMBL8327787 | 0.69 | CCR5 (0.34) | SLC18A3NPSR1KDM4EATMTDP1 | |
| SCHEMBL22553535 | 0.67 | SLC18A3 (0.41) | SLC18A3NPSR1KDM4EATMTDP1 | |
| SCHEMBL22553534 | 0.67 | SLC18A3 (0.41) | SLC18A3NPSR1KDM4EATMTDP1 | |
| SCHEMBL15191721 | 0.67 | SLC18A3 (0.41) | SLC18A3NPSR1KDM4EATMTDP1 | |
| SCHEMBL22553624 | 0.64 | LMNA (0.43) | SLC18A3NPSR1OPRM1ALDH1A1LMNA | |
| SCHEMBL12745062 | 0.61 | ALDH1A1 (0.46) | SLC18A3DDB1CRBNALDH1A1KCNH2 | |
| SCHEMBL24434663 | 0.60 | OPRM1 (0.58) | NPSR1OPRM1OPRL1ALDH1A1LMNA | |
| SCHEMBL10709827 | 0.60 | SLC6A2 (0.56) | SLC18A3NPSR1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL11115148 | 0.60 | SLC6A2 (0.56) | SLC18A3NPSR1KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925624-A | ANTIINFLAMMATORY AGENTS TREATING PATIENTS WITH INFLAMMATORY CONDITIONS SUSCEPTIBLE TO LEUKOCYTE-INDUCED TISSUE DAMAGE | GLAXO GROUP LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |