Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 5/20 | 0.46 |
| ▸ | CDK2 | P24941 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329082 | 0.84 | CCNA2 (0.48) | CCNA2CDK2CYP1A2CYP3A4MEN1 | |
| SCHEMBL8325184 | 0.81 | CCNA2 (0.62) | CCNA2CDK2CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL8326420 | 0.81 | CCNA2 (0.67) | CCNA2CDK2 | |
| SCHEMBL8580105 | 0.79 | CCNA2 (0.44) | CCNA2CDK2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8329431 | 0.78 | CCNA2 (0.44) | CCNA2CDK2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8330251 | 0.75 | DUSP10 (0.45) | CCNA2CDK2CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL8327091 | 0.74 | CCNA2 (0.51) | CCNA2CDK2CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL8326631 | 0.72 | KDM4E (0.43) | CCNA2CDK2CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL8329211 | 0.72 | KDM4E (0.43) | CCNA2CDK2CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL10999619 | 0.69 | KMT2A (0.60) | CYP1A2ALDH1A1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | claimed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | claimed |
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |