Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 5/20 | 0.44 |
| ▸ | CDK2 | P24941 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327052 | 0.87 | CDK2 (0.35) | CCNA2CDK2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8328773 | 0.83 | HRH4 (0.39) | CCNA2CDK2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8327878 | 0.82 | CCNA2 (0.34) | CCNA2CDK2CYP1A2CYP2C19KDM4E | |
| SCHEMBL8330251 | 0.82 | DUSP10 (0.45) | CCNA2CDK2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8329211 | 0.81 | KDM4E (0.43) | CCNA2CDK2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8326151 | 0.81 | CYP1A2 (0.41) | CCNA2CDK2CYP1A2CYP2C19KDM4E | |
| SCHEMBL8325184 | 0.81 | CCNA2 (0.62) | CCNA2CDK2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8329082 | 0.81 | CCNA2 (0.48) | CCNA2CDK2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8326389 | 0.79 | CCNT1 (0.39) | CDK2KDM4ECYP19A1 | |
| SCHEMBL8326631 | 0.78 | KDM4E (0.43) | CCNA2CDK2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | claimed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | claimed |
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |