Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 8/20 | 0.48 |
| ▸ | CDK2 | P24941 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325184 | 0.85 | CCNA2 (0.62) | CCNA2CDK2MEN1KMT2AKDM4E | |
| SCHEMBL8326420 | 0.84 | CCNA2 (0.67) | CCNA2CDK2 | |
| SCHEMBL8327901 | 0.84 | CCNA2 (0.46) | CCNA2CDK2MEN1KMT2AKDM4E | |
| SCHEMBL8580105 | 0.82 | CCNA2 (0.44) | CCNA2CDK2KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8329431 | 0.81 | CCNA2 (0.44) | CCNA2CDK2KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8330251 | 0.78 | DUSP10 (0.45) | CCNA2CDK2MEN1KMT2AKDM4E | |
| SCHEMBL8327091 | 0.77 | CCNA2 (0.51) | CCNA2CDK2MEN1KMT2AKDM4E | |
| SCHEMBL8329211 | 0.75 | KDM4E (0.43) | CCNA2CDK2MEN1KMT2AKDM4E | |
| SCHEMBL8326631 | 0.75 | KDM4E (0.43) | CCNA2CDK2MEN1KMT2AKDM4E | |
| SCHEMBL8328773 | 0.71 | HRH4 (0.39) | CCNA2CDK2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | claimed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | claimed |
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |