Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.64 |
| ▸ | ALPG | P10696 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.55 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.55 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17329391 | 0.84 | KDM4E (0.59) | ALPLALPGRAB9ASMN1; SMN2TP53 | |
| SCHEMBL7217435 | 0.84 | BCHE (0.60) | ALPLALPGRAB9ASMN1; SMN2TP53 | |
| SCHEMBL5845732 | 0.83 | BCHE (0.60) | ALPLALPGRAB9ASMN1; SMN2TP53 | |
| SCHEMBL12948201 | 0.83 | SMN1; SMN2 (0.59) | ALPLALPGRAB9ASMN1; SMN2TP53 | |
| SCHEMBL6764617 | 0.82 | BCHE (0.65) | ALPLALPGRAB9ASMN1; SMN2TP53 | |
| SCHEMBL5846138 | 0.81 | KCNH2 (0.60) | ALPLALPGRAB9ASMN1; SMN2TP53 | |
| SCHEMBL5845974 | 0.80 | BCHE (0.57) | ALPLALPGRAB9ASMN1; SMN2TP53 | |
| SCHEMBL24549684 | 0.79 | RAB9A (0.60) | ALPLALPGRAB9ASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL27647756 | 0.78 | BCHE (0.69) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL204726 | 0.78 | NPC1 (0.73) | RAB9ASMN1; SMN2TP53NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129256-A1 | SELECTIVE HDAC6 INHIBITOR | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2022-06-23 | — | — | WO | disclosed |
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |
| EP-0195947-B1 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1996-04-24 | — | — | EP | disclosed |
| CN-1017335-B | PROCESS FOR PREPARING BETA-LACTAM ANTIBIOTICS | BAYER AG (DE) | 1992-07-08 | — | — | CN | disclosed |
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0195947-A2 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |