Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20561440 | 0.92 | MAPT (0.75) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL22470213 | 0.90 | CACNA1G (0.60) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL22470286 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL1232898 | 0.86 | LMNA (0.71) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL7211361 | 0.86 | POLB (0.62) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL9212097 | 0.86 | POLB (0.62) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL5487156 | 0.84 | POLB (0.64) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL8329251 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL29040013 | 0.83 | PARP1 (0.65) | KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL5395748 | 0.83 | MAPT (0.83) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |