Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089178 | 0.75 | KMT2A (0.42) | KMT2ASMN1; SMN2NPSR1LOXL2PPARA | |
| SCHEMBL777758 | 0.70 | DYRK1A (0.52) | KMT2ASMN1; SMN2NPSR1LOXL2AGPAT2 | |
| SCHEMBL779852 | 0.67 | NPC1 (0.54) | KMT2ASMN1; SMN2PPARAALDH1A1CYP1A2 | |
| SCHEMBL780242 | 0.65 | SMN1; SMN2 (0.61) | KMT2ASMN1; SMN2NPSR1LOXL2PPARA | |
| SCHEMBL19965725 | 0.64 | HSD17B10 (0.49) | KMT2ASMN1; SMN2NPSR1ALDH1A1HTT | |
| SCHEMBL6092062 | 0.64 | KMT2A (0.52) | KMT2ASMN1; SMN2PPARAALDH1A1HTT | |
| SCHEMBL799569 | 0.64 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2NPSR1LOXL2ALDH1A1 | |
| SCHEMBL30189802 | 0.64 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2NPSR1LOXL2ALDH1A1 | |
| SCHEMBL31630664 | 0.61 | NPC1 (0.52) | KMT2ASMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1121389 | 0.61 | NPC1 (0.50) | KMT2ASMN1; SMN2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067529-A1 | INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |