Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328438 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL8327668 | 0.92 | GRIA2 (0.41) | ALDH1A1TSHRHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL8327673 | 0.92 | GRIA2 (0.41) | ALDH1A1TSHRHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL8323410 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL8323407 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL8327882 | 0.77 | GRIA2 (0.43) | ALDH1A1TSHRHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL8328629 | 0.71 | GRIA4 (0.38) | ALDH1A1TSHRHSD17B10GRIA2GRIA4 | |
| SCHEMBL8328635 | 0.71 | GRIA4 (0.38) | ALDH1A1TSHRHSD17B10GRIA2GRIA4 | |
| SCHEMBL8323908 | 0.70 | ALDH1A1 (0.49) | ALDH1A1HSD17B10RAB9ANPC1GRIA2 | |
| SCHEMBL8328148 | 0.69 | GRIA4 (0.41) | ALDH1A1TSHRHSD17B10GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |