Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328828 | 0.76 | AOC3 (0.45) | ALDH1A1L3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL8327964 | 0.72 | GRIA2 (0.39) | ALDH1A1L3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL8327668 | 0.71 | GRIA2 (0.41) | ALDH1A1L3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL9710841 | 0.70 | GSK3B (0.50) | ALDH1A1KDM4ELMNAMAPK1PGR | |
| SCHEMBL8328438 | 0.70 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KDM4EMAPK1GRIA2 | |
| SCHEMBL8328148 | 0.69 | GRIA4 (0.41) | ALDH1A1L3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL8328146 | 0.69 | GRIA4 (0.41) | ALDH1A1L3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL8326586 | 0.67 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL9710619 | 0.67 | GSK3B (0.46) | ALDH1A1KDM4EMAPK1PGRGSK3A | |
| SCHEMBL9711058 | 0.67 | KDM4E (0.48) | ALDH1A1L3MBTL1KDM4ELMNAGRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |