Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327308 | 0.82 | KMT2A (0.45) | CYP1A2DRD2DRD3HTR1DKMT2A | |
| SCHEMBL9979558 | 0.77 | PPARD (0.53) | DRD2DRD3HTR1D | |
| SCHEMBL4760401 | 0.75 | PPARD (0.46) | DRD2DRD3HTR1D | |
| SCHEMBL5533444 | 0.72 | DGAT1 (0.40) | DRD2DRD3HTR1DDRD1DRD4 | |
| SCHEMBL2254801 | 0.72 | DGAT1 (0.40) | DRD2DRD3HTR1DDRD1DRD4 | |
| SCHEMBL14061800 | 0.72 | CYP24A1 (0.48) | DRD2DRD3HTR1D | |
| SCHEMBL2254799 | 0.72 | DGAT1 (0.40) | DRD2DRD3HTR1DDRD1DRD4 | |
| SCHEMBL2253838 | 0.71 | DGAT1 (0.39) | DRD2DRD3HTR1DDRD1DRD4 | |
| SCHEMBL2253842 | 0.71 | DGAT1 (0.39) | DRD2DRD3HTR1DDRD1DRD4 | |
| SCHEMBL5536891 | 0.71 | DGAT1 (0.39) | DRD2DRD3HTR1DDRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |