Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.45 |
| ▸ | ITGAV | P06756 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13465239 | 0.83 | HCAR2 (0.49) | TNKSTNKS2MAPK1SMN1; SMN2LMNA | |
| SCHEMBL6945050 | 0.79 | ITGB3 (0.47) | MAPK1ITGB3ITGAVALDH1A1MAPT | |
| SCHEMBL1624031 | 0.76 | TNKS (0.50) | TNKSTNKS2SMN1; SMN2LMNAPLAU | |
| SCHEMBL23508126 | 0.76 | AAK1 (0.49) | TNKSTNKS2MAPK1ITGB3ITGAV | |
| SCHEMBL3257381 | 0.75 | TNKS (0.52) | TNKSTNKS2LMNAALDH1A1MAPT | |
| SCHEMBL13933317 | 0.75 | RAB9A (0.50) | TNKSTNKS2MAPK1SMN1; SMN2LMNA | |
| SCHEMBL3825080 | 0.75 | RAB9A (0.47) | TNKSTNKS2MAPK1SMN1; SMN2LMNA | |
| SCHEMBL23508272 | 0.75 | TNKS (0.46) | TNKSTNKS2MAPK1ITGB3ITGAV | |
| SCHEMBL4887144 | 0.75 | RIPK1 (0.47) | TNKSTNKS2MAPK1SMN1; SMN2LMNA | |
| SCHEMBL30103173 | 0.74 | AAK1 (0.59) | TNKSTNKS2MAPK1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |