Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8328549 | 0.98 | SLC6A4 (0.51) | SLC6A4SLC6A3BCAT2LMNAPTGS2 | |
| SCHEMBL32689453 | 0.84 | BCAT2 (0.63) | BCAT2LMNAWDR5F2F10 | |
| SCHEMBL1034554 | 0.84 | BCAT2 (0.63) | BCAT2LMNAWDR5F2F10 | |
| Hydrochloric Acid SCHEMBL27450056 | 0.82 | BCAT2 (0.61) | BCAT2LMNAWDR5F2F10 | |
| Hydrochloric Acid SCHEMBL31621742 | 0.82 | BCAT2 (0.61) | BCAT2LMNAWDR5F2F10 | |
| Ammonia Solution, Strong SCHEMBL29131061 | 0.82 | BCAT2 (0.61) | BCAT2LMNAWDR5F2F10 | |
| SCHEMBL7151686 | 0.82 | BCAT2 (0.55) | BCAT2LMNAWDR5F2F10 | |
| SCHEMBL8343625 | 0.81 | SLC6A4 (0.53) | SLC6A4SLC6A3BCAT2PTGS2PTGS1 | |
| SCHEMBL197002 | 0.81 | BCAT2 (0.71) | SLC6A4SLC6A3BCAT2PTGS2PTGS1 | |
| SCHEMBL28216060 | 0.81 | SLC6A4 (0.53) | SLC6A4SLC6A3BCAT2LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915879-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998001449-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-01-15 | — | — | WO | disclosed |