SCHEMBL197002

SCHEMBL197002

NC(=O)c1ccccc1-c1ccc(Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.71
SLC6A4 P31645 1/20 0.62
SLC6A3 Q01959 1/20 0.62
FGFR1 P11362 1/20 0.54
SRC P12931 1/20 0.54
FGFR2 P21802 1/20 0.54
FGFR4 P22455 1/20 0.54
FGFR3 P22607 1/20 0.54
CASP1 P29466 1/20 0.51
PARP1 P09874 2/20 0.50
CYP2C19 P33261 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
CHEK1 O14757 1/20 0.48
FPR2 P25090 1/20 0.47
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
AGTR1 P30556 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28270443 0.98 BCAT2 (0.69) BCAT2SLC6A4SLC6A3FGFR1SRC
SCHEMBL5878337 0.90 BCAT2 (0.87) BCAT2SLC6A4SLC6A3PARP1CHEK1
SCHEMBL30582476 0.88 BCAT2 (0.83) BCAT2SLC6A4SLC6A3CHEK1MAPT
SCHEMBL10631889 0.84 SLC6A4 (0.66) BCAT2SLC6A4SLC6A3FGFR1SRC
SCHEMBL31140008 0.84 BCAT2 (0.92) BCAT2PARP1CHEK1MAPTMEN1
SCHEMBL6590788 0.84 IKBKB (0.52) BCAT2SLC6A4SLC6A3FGFR1SRC
SCHEMBL29427545 0.84 BCAT2 (1.00) BCAT2FGFR1SRCFGFR2FGFR4
SCHEMBL132986 0.84 BCAT2 (1.00) BCAT2FGFR1SRCFGFR2FGFR4
SCHEMBL16149659 0.84 BCAT2 (0.91) BCAT2PARP1CHEK1MAPTMEN1
SCHEMBL3241447 0.83 BCAT2 (0.63) BCAT2SLC6A4SLC6A3CASP1CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080689-A Botrytis cinerea method for synthesizing amine 浙江新安化工集团股份有限公司 2024-12-06 CN claimed
CN-113831280-B Preparation method of boscalid 上海埃农生物科技有限公司 2023-08-15 CN claimed
CN-113831280-A Preparation method of boscalid 上海埃农生物科技有限公司 2021-12-24 CN claimed
CN-109970571-B Synthesis process of 2- (4-chlorphenyl) aniline 安徽丰乐农化有限责任公司 2021-10-19 CN claimed
CN-109232411-B Method for preparing boscalid 广东广康生化科技股份有限公司 2021-10-01 CN claimed
CN-111662184-A Synthetic method of boscalid intermediate 2- (4' -chlorphenyl) aniline 广东广康生化科技股份有限公司 2020-09-15 CN claimed
CN-109970571-A A kind of synthesis technology of 2- (4- chlorphenyl) aniline 安徽丰乐农化有限责任公司 2019-07-05 CN claimed
CN-109232411-A A method of preparing boscalid 广东广康生化科技股份有限公司 2019-01-18 CN claimed
EP-1252140-B1 PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-05-13 EP claimed
EP-0273444-A2 Use of carboxamide compounds for the preparation of a medicament for treating hyperlipidemia OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1988-07-06 EP claimed
CN-119080689-A Botrytis cinerea method for synthesizing amine 浙江新安化工集团股份有限公司 2024-12-06 CN disclosed
CN-118048636-B Electrocatalytic synthesis method for N-aryl amide 平顶山学院 2024-09-13 CN disclosed
CN-118048636-A Electrocatalytic synthesis method for N-aryl amide 平顶山学院 2024-05-17 CN disclosed
CN-115286514-B Preparation method of 4' -chloro-2-aminobiphenyl sulfate 山东京博农化科技股份有限公司 2024-01-12 CN disclosed
CN-115057794-B Method for removing methylation of cerium catalytic oxidation amide by visible light induction 桂林理工大学 2023-11-17 CN disclosed
EP-1235811-B1 PYRAZOLECARBOXAMIDE AND PYRAZOLETHIOAMIDE AS FUNGICIDE SYNGENTA PARTICIPATIONS AG (CH) 2005-06-01 EP disclosed
EP-1235811-A1 PYRAZOLECARBOXAMIDE AND PYRAZOLETHIOAMIDE AS FUNGICIDE Syngenta Participations AG (CH) 2002-09-04 EP disclosed
WO-2001042223-A1 PYRAZOLECARBOXAMIDE AND PYRAZOLETHIOAMIDE AS FUNGICIDE SYNGENTA PARTICIPATIONS AG (CH) 2001-06-14 WO disclosed
EP-0273444-A2 Use of carboxamide compounds for the preparation of a medicament for treating hyperlipidemia OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1988-07-06 EP disclosed
US-4093648-A ANTIANAPHYLACTIC AGENTS RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1978-06-06 US disclosed