Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.47 |
| ▸ | RXRG | P48443 | 10/20 | 0.40 |
| ▸ | RXRB | P28702 | 9/20 | 0.40 |
| ▸ | RARG | P13631 | 7/20 | 0.38 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.38 |
| ▸ | GNRHR | P30968 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124020 | 0.77 | RXRA (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8200207 | 0.77 | RARG (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8200200 | 0.77 | RARG (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8330612 | 0.75 | RARA (0.58) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL22001266 | 0.74 | RXRA (0.54) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8529655 | 0.73 | RXRA (0.49) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7931914 | 0.73 | RXRA (0.49) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7622765 | 0.71 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL9626984 | 0.70 | RXRA (0.47) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7568695 | 0.69 | RXRA (0.53) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917082-A | 2,4-pentadienoic acid derivatives having retinoid-like biological activity | ALLERGAN SALES, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5817836-A | 2,4-pentadienoic acid derivatives having retinoid-like biological activity | ALLERGAN (US) | 1998-10-06 | — | — | US | disclosed |
| US-5780647-A | 2,4-Pentadienoic acid derivatives having retinoid-like biological activity | ALLERGAN (US) | 1998-07-14 | — | — | US | disclosed |
| US-5675033-A | FOR TREATMENT OF SKIN DISORDERS | ALLERGAN (US) | 1997-10-07 | — | — | US | disclosed |