Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599657 | 0.80 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL5790830 | 0.71 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL7439961 | 0.70 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL6297565 | 0.69 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL25466687 | 0.68 | GPR84 (0.44) | CRHR1 | |
| SCHEMBL25466684 | 0.68 | GPR84 (0.44) | CRHR1 | |
| SCHEMBL7439953 | 0.67 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL6295712 | 0.66 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL6302106 | 0.66 | CRHR1 (0.87) | CRHR1 | |
| SCHEMBL6301715 | 0.65 | CRHR1 (0.82) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923582-A1 | SUBSTITUTED 6,5-HETERO-BICYCLIC DERIVATIVES | PFIZER INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008847-A1 | SUBSTITUTED 6,5-HETERO-BICYCLIC DERIVATIVES | PFIZER INC. (US) | 1998-03-05 | — | — | WO | disclosed |