Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352235 | 0.74 | HCAR3 (0.65) | HCAR3HPGDFGFR1TSHRNPSR1 | |
| SCHEMBL1306713 | 0.73 | HCAR3 (0.60) | HCAR3HPGDFGFR1TSHRNPSR1 | |
| SCHEMBL8464959 | 0.73 | ITGB3 (0.44) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL599310 | 0.71 | HCAR3 (0.65) | HCAR3HPGDFGFR1TSHRNPSR1 | |
| SCHEMBL20819211 | 0.71 | FGFR1 (0.56) | HCAR3HPGDFGFR1TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL7330424 | 0.70 | HCAR3 (0.63) | HCAR3HPGDFGFR1TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL9631739 | 0.70 | FGFR1 (0.59) | HCAR3HPGDFGFR1TSHRNPSR1 | |
| SCHEMBL2297233 | 0.70 | HCAR3 (0.55) | HCAR3HPGDFGFR1TSHRNPSR1 | |
| SCHEMBL6441326 | 0.70 | HCAR3 (0.76) | HCAR3HPGDFGFR1NPSR1ALDH1A1 | |
| SCHEMBL30937457 | 0.69 | HCAR3 (0.61) | HCAR3HPGDFGFR1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |