Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14713128 | 0.78 | SIGMAR1 (0.36) | HTR2CSIGMAR1DRD2OPRM1KDM1A | |
| SCHEMBL8707482 | 0.74 | HTR2C (0.38) | HTR2CGAA | |
| SCHEMBL8588820 | 0.72 | DPP9 (0.32) | GNRHRKCNH2SIGMAR1KDM1A | |
| SCHEMBL16860861 | 0.70 | NOTUM (0.36) | GNRHRKCNH2SIGMAR1GAAOPRM1 | |
| SCHEMBL17444517 | 0.69 | NOTUM (0.36) | KCNH2SIGMAR1GAANOTUMKDM1A | |
| SCHEMBL38332 | 0.69 | NPY5R (0.55) | NPY5RNOTUM | |
| SCHEMBL30051797 | 0.69 | NPY5R (0.55) | NPY5RNOTUM | |
| SCHEMBL3991429 | 0.68 | EPHX2 (0.33) | — | |
| SCHEMBL8845622 | 0.68 | SIGMAR1 (0.47) | HTR2CSIGMAR1DRD2OPRM1KDM1A | |
| Hydrochloric Acid SCHEMBL7123289 | 0.68 | NPY5R (0.54) | NPY5RNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937076-A1 | SUBSTITUTED OXIMES, HYDRAZONES AND OLEFINS AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998020010-A1 | SUBSTITUTED OXIMES, HYDRAZONES AND OLEFINS AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1998-05-14 | — | — | WO | disclosed |