Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 7/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580793 | 0.89 | GNRHR (0.41) | HTR2CELANETACR1F2CTSG | |
| SCHEMBL16539832 | 0.78 | HTR2C (0.43) | HTR2CNPC1GAAMAPK1RAB9A | |
| SCHEMBL8469385 | 0.76 | GHSR (0.56) | TACR1 | |
| SCHEMBL7500323 | 0.76 | GHSR (0.55) | TACR1 | |
| SCHEMBL1670310 | 0.74 | HTR2C (0.49) | HTR2CTACR1NPC1GAAMAPK1 | |
| SCHEMBL8328802 | 0.74 | GNRHR (0.40) | HTR2CGAA | |
| SCHEMBL6649033 | 0.73 | HTR2C (0.40) | HTR2CELANENPC1GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL8814693 | 0.70 | BACE1 (0.45) | HTR2CTACR1BACE1TSHRNPC1 | |
| SCHEMBL5598985 | 0.67 | MTNR1A (0.36) | HTR2CMAPK1 | |
| SCHEMBL24433396 | 0.67 | TSHR (0.43) | HTR2CTACR1BACE1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018762-A1 | NEW DERIVATIVES OF DIVERSELY SUBSTITUTED CYCLICAL AMIDE SELECTIVE ANTAGONISTS OF THE HUMAN RECEPTOR NK3, PROCESS FOR OBTAINING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1998-05-07 | — | — | WO | disclosed |