Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963272 | 0.92 | GSK3B (0.32) | DHODHGSK3BFPR1FPR2PDE4A | |
| SCHEMBL7952322 | 0.91 | SQOR (0.34) | DHODHGSK3BFPR1FPR2 | |
| SCHEMBL7961829 | 0.91 | IDO1 (0.35) | IDO1GSK3BFPR1FPR2 | |
| SCHEMBL8325837 | 0.90 | DHODH (0.38) | DHODHIDO1NPC1RAB9A | |
| SCHEMBL7965124 | 0.82 | DHODH (0.32) | DHODH | |
| SCHEMBL7961118 | 0.81 | HSP90AA1 (0.35) | IDO1GSK3BFPR1FPR2 | |
| SCHEMBL7965202 | 0.81 | HPGD (0.32) | DHODH | |
| SCHEMBL7952692 | 0.81 | IDO1 (0.36) | DHODHIDO1GSK3B | |
| SCHEMBL7962634 | 0.81 | CYP11B2 (0.36) | — | |
| SCHEMBL8330546 | 0.80 | CYP11B2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | claimed |