Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.44 |
| ▸ | FNTB | P49356 | 5/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147908 | 0.80 | FNTA (0.61) | FNTAFNTBPGGT1BADRB2DRD2 | |
| SCHEMBL8147898 | 0.77 | FNTA (0.61) | FNTAFNTBPGGT1B | |
| SCHEMBL8143455 | 0.77 | AR (0.36) | AR | |
| SCHEMBL8329025 | 0.76 | FNTA (0.42) | FNTAFNTBPGGT1BADRB2DRD2 | |
| SCHEMBL8155625 | 0.74 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL6477825 | 0.68 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL501379 | 0.67 | PRKCA (0.37) | S1PR1 | |
| SCHEMBL16954928 | 0.63 | AR (0.46) | FNTAFNTBPGGT1BS1PR1S1PR3 | |
| SCHEMBL4783565 | 0.63 | PRKCI (0.43) | — | |
| SCHEMBL2997723 | 0.63 | SNCA (0.49) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951285-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998029119-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1998-07-09 | — | — | WO | disclosed |