SCHEMBL6928751

SCHEMBL6928751

CCOC1(c2c[c]ccc2)CCNCC1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 5/20 0.40
OPRD1 P41143 2/20 0.40
OPRK1 P41145 2/20 0.40
OPRL1 P41146 2/20 0.40
TACR1 P25103 3/20 0.33
HTR2A P28223 1/20 0.31
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6932312 0.88 OPRM1 (0.42) OPRM1OPRD1OPRK1OPRL1TACR1
SCHEMBL6931872 0.86 OPRM1 (0.35) OPRM1OPRD1OPRK1OPRL1TACR1
SCHEMBL28818442 0.83 OPRM1 (0.39) OPRM1OPRD1OPRK1OPRL1
SCHEMBL8329089 0.82 OPRM1 (0.55) OPRM1OPRD1OPRK1OPRL1TACR1
SCHEMBL7373707 0.81 OPRM1 (0.31) OPRM1TACR1
Hydrochloric Acid SCHEMBL18424795 0.81 OPRM1 (0.54) OPRM1OPRD1OPRK1OPRL1TACR1
SCHEMBL28818483 0.78 OPRM1 (0.35) OPRM1OPRD1OPRK1OPRL1
SCHEMBL18895934 0.73 DRD2 (0.50) OPRM1OPRD1OPRK1OPRL1
Hydrochloric Acid SCHEMBL29041993 0.72 OPRM1 (0.38) OPRM1OPRD1OPRK1OPRL1TACR1
SCHEMBL6932255 0.72 OPRM1 (0.42) OPRM1TACR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1366066-A2 CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-12-03 EP disclosed
WO-2002072621-A2 CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-09-19 WO disclosed