Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548343 | 0.92 | EDNRA (0.45) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6580198 | 0.83 | EDNRA (0.44) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6580025 | 0.83 | KDM4E (0.36) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6579920 | 0.82 | EDNRA (0.46) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6580278 | 0.79 | EDNRA (0.45) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8434266 | 0.77 | EDNRA (0.44) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7494883 | 0.76 | EDNRA (0.46) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7501396 | 0.76 | EDNRA (0.45) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6582508 | 0.76 | EDNRA (0.43) | EDNRAALDH1A1EDNRB | |
| SCHEMBL6582430 | 0.75 | EDNRA (0.43) | EDNRAALDH1A1SMN1; SMN2EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |