Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | EDNRB | P24530 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329175 | 0.83 | EDNRA (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL7548343 | 0.77 | EDNRA (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL6580198 | 0.75 | EDNRA (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL6582681 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL6580278 | 0.73 | EDNRA (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL6577451 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL6579920 | 0.72 | EDNRA (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL6580281 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL6579951 | 0.71 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA | |
| SCHEMBL8323946 | 0.71 | EDNRB (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804435-B1 | NOVEL IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2004-03-10 | — | — | EP | disclosed |
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |