Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | DHODH | Q02127 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328993 | 0.84 | MEN1 (0.51) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL8327199 | 0.81 | KDM4E (0.74) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL6183169 | 0.80 | DHODH (0.85) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL8231320 | 0.79 | DHODH (0.70) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL8326298 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL8321360 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL1898810 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL8328431 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL8321335 | 0.75 | ALDH1A1 (0.79) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL2783593 | 0.75 | KDM4E (0.79) | KDM4EALDH1A1HSD17B10DHODHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |